LASEK Refractive Surgery After Corneal Transplantation With And Without Intraoperative Mitomycin-C

Authors

  • Paul Huang Queen's University

Abstract

Objectives: To evaluate the effectiveness and complications of laser-assisted subepithelial keratectomy (LASEK) with and without mitomycin-C following corneal transplantation.

Methods: Retrospective study comprising 94 eyes of 84 patients. Mean age was 56 years. 50 patients (58 eyes) received LASEK without MMC (NOMMC) and 34 patients (36 eyes) received LASEK with MMC (MMC).

Results: At last follow-up (average 11.48 months post-laser), the mean SE decreased from -2.84 (D) ± 3.98 (SD) to -0.41 D ± 3.41 in the NOMMC group and -2.19 D ± 4.85 to -0.40 D ± 1.88 in the MMC group. Preoperative uncorrected distance visual acuity (UDVA) was 1.56 ± 0.57 (n = 57) and 1.27 ± 0.55 (n = 28), respectively and postoperative UDVA, 0.91 ± 0.58 (n = 57) and 0.81 ± 0.53 (n = 33). Spherical equivalence and UDVA improved significantly for both groups (P < .01). The mean haze (0 to 3 scale) at follow-up was 0.64 ± 0.86 in the NOMMC group, and 0.03 ± 0.12 in the MMC group.

Conclusion: LASEK with and without MMC effectively reduced refractive errors following corneal transplantation. No significant difference in visual outcomes between groups. Significant difference in corneal haze between the two groups (P < .01).

Author Biography

Paul Huang, Queen's University

Faculty of Medicine, Medical Degree Class of 2015

References

1. Bochmann & Schipper. J Cataract Refract Surg. 32: 923-8, 2006.

2. Rajan, MS, et al. J Cataract Refract Surg. 32: 949-57, 2006.

3. Chang & Hardten. Curr Opin Ophthalmol. 16: 251-255, 2005.

4. Astle W, et al. J Cataract Refract Surg. 30: 2529-35, 2004.

5. O'Doherty M, et al. J Cataract Refract Surg. 23: 133-8, 2007.

6. Nakano E, et al. J Cataract Refract Surg. 23: S1021, 2007.

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Published

2013-11-19

Issue

Vol. 3 No. 2 (2013)

Section

Extended Abstracts

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